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Publications

Our publications focus on research related to potential of the Wnt pathway to address critical drivers of disease.

January 1, 2022 | Cellular and Molecular Gastroenterology and Hepatology, 14, 435-464 (2022)
Robust Colonic Epithelial Regeneration and Amelioration of Colitis via FZD-Specific Activation of Wnt Signaling
May 31, 2021 | Nature Communications (2021)
Development of selective bispecific Wnt mimetics for bone loss and repair
August 18, 2020 | Sci. Rep, 10(1):13951 (2020)
Tissue-targeted R-spondin mimetics for liver regeneration
May 21, 2020 | Cell Chemical Biology, Online, (2020)
Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements
November 29, 2018 | Cell (2018)
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
November 10, 2017 | Annu. Rev. Pathol. Mech. Dis. (2018)
Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology
June 1, 2017 | Cell, 169 (6), 985-999 (2017)
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
May 3, 2017 | Nature, 545, 234-237 (2017)
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
October 27, 2016 | Nature Cell Biology (2015)
The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size
October 1, 2016 | Current Topics in Developmental Biology (2016)
Frizzled Receptors in Development and Disease
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